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Access of protective antiviral antibody to neuronal tissues requires CD4 T cell help
Circulating antibodies can access most tissues to mediate surveillance and elimination of invading pathogens. Immunopriviledged tissues such as the brain and the peripheral nervous system, are shielded from plasma proteins, by the blood-brain barrier(1) and blood nerve barrier(2), respectively. Yet,...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4883597/ https://www.ncbi.nlm.nih.gov/pubmed/27225131 http://dx.doi.org/10.1038/nature17979 |