Cargando…

EBI2 augments Tfh cell fate by promoting interaction with IL2-quenching dendritic cells

T follicular helper (Tfh) cells are a CD4 T cell subset that is important for supporting plasma cell and germinal center (GC) responses(1,2). The initial induction of Tfh cell properties occurs within the first few days following activation by antigen recognition on dendritic cells (DCs), though how...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Jianhua, Lu, Erick, Yi, Tangsheng, Cyster, Jason G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4883664/
https://www.ncbi.nlm.nih.gov/pubmed/27147029
http://dx.doi.org/10.1038/nature17947