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Alpha 1 Antitrypsin Inhibits Dendritic Cell Activation and Attenuates Nephritis in a Mouse Model of Lupus

Systemic lupus erythematosus (SLE) is an autoimmune disorder with a worldwide distribution and considerable mortality and morbidity. Although the pathogenesis of this disease remains elusive, over-reactive dendritic cells (DCs) play a critical role in the disease development. It has been shown that...

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Detalles Bibliográficos
Autores principales: Elshikha, Ahmed S., Lu, Yuanqing, Chen, Mong-Jen, Akbar, Mohammad, Zeumer, Leilani, Ritter, Andrea, Elghamry, Hanaa, Mahdi, Mahmoud A., Morel, Laurence, Song, Sihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4883758/
https://www.ncbi.nlm.nih.gov/pubmed/27232337
http://dx.doi.org/10.1371/journal.pone.0156583