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Keap1-Independent Regulation of Nrf2 Activity by Protein Acetylation and a BET Bromodomain Protein
Mammalian BET proteins comprise a family of bromodomain-containing epigenetic regulators with complex functions in chromatin organization and gene regulation. We identified the sole member of the BET protein family in Drosophila, Fs(1)h, as an inhibitor of the stress responsive transcription factor...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4883770/ https://www.ncbi.nlm.nih.gov/pubmed/27233051 http://dx.doi.org/10.1371/journal.pgen.1006072 |