Cargando…

Keap1-Independent Regulation of Nrf2 Activity by Protein Acetylation and a BET Bromodomain Protein

Mammalian BET proteins comprise a family of bromodomain-containing epigenetic regulators with complex functions in chromatin organization and gene regulation. We identified the sole member of the BET protein family in Drosophila, Fs(1)h, as an inhibitor of the stress responsive transcription factor...

Descripción completa

Detalles Bibliográficos
Autores principales: Chatterjee, Nirmalya, Tian, Min, Spirohn, Kerstin, Boutros, Michael, Bohmann, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4883770/
https://www.ncbi.nlm.nih.gov/pubmed/27233051
http://dx.doi.org/10.1371/journal.pgen.1006072