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Control of Ca(2+) Influx and Calmodulin Activation by SK-Channels in Dendritic Spines
The key trigger for Hebbian synaptic plasticity is influx of Ca(2+) into postsynaptic dendritic spines. The magnitude of [Ca(2+)] increase caused by NMDA-receptor (NMDAR) and voltage-gated Ca(2+) -channel (VGCC) activation is thought to determine both the amplitude and direction of synaptic plastici...
Autores principales: | Griffith, Thom, Tsaneva-Atanasova, Krasimira, Mellor, Jack R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4883788/ https://www.ncbi.nlm.nih.gov/pubmed/27232631 http://dx.doi.org/10.1371/journal.pcbi.1004949 |
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