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The FBPase Encoding Gene glpX Is Required for Gluconeogenesis, Bacterial Proliferation and Division In Vivo of Mycobacterium marinum

Lipids have been identified as important carbon sources for Mycobacterium tuberculosis (Mtb) to utilize in vivo. Thus gluconeogenesis bears a key role for Mtb to survive and replicate in host. A rate-limiting enzyme of gluconeogenesis, fructose 1, 6-bisphosphatase (FBPase) is encoded by the gene glp...

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Detalles Bibliográficos
Autores principales: Tong, Jingfeng, Meng, Lu, Wang, Xinwei, Liu, Lixia, Lyu, Liangdong, Wang, Chuan, Li, Yang, Gao, Qian, Yang, Chen, Niu, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4883791/
https://www.ncbi.nlm.nih.gov/pubmed/27233038
http://dx.doi.org/10.1371/journal.pone.0156663