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Targeting met mediated epithelial-mesenchymal transition in the treatment of breast cancer
Mesenchymal epithelial transition factor receptor (Met) is a receptor tyrosine kinase that plays a critical role in promoting cancer cell malignant progression. Met is activated by its ligand hepatocyte growth factor (HGF). HGF-dependent Met activation plays an important role in stimulating epitheli...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Springer Berlin Heidelberg
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4883993/ https://www.ncbi.nlm.nih.gov/pubmed/26932375 http://dx.doi.org/10.1186/s40169-014-0030-5 |