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Preliminary clinical assessment of the relationship between tumor alphavbeta3 integrin and perfusion in patients studied with [(18)F]fluciclatide kinetics and [(15)O]H(2)O PET

BACKGROUND: [(18)F]fluciclatide, a peptide ligand with high affinity for αvβ3/αvβ5 integrins, is a proposed biomarker of tumor angiogenesis. The study rationale was to perform a preliminary evaluation of the relationship between tumor [(18)F]fluciclatide uptake and perfusion by [(15)O]H(2)O PET. MET...

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Detalles Bibliográficos
Autores principales: Kenny, Laura M, Tomasi, Giampaolo, Turkheimer, Federico, Larkin, James, Gore, Martin, Brock, Cathryn S, Mangar, Stephen, Aboagye, Eric O
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884000/
https://www.ncbi.nlm.nih.gov/pubmed/26055935
http://dx.doi.org/10.1186/s13550-014-0030-x