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Transcriptional factor snail controls tumor neovascularization, growth and metastasis in mouse model of human ovarian carcinoma

BACKGROUND: Snail, a transcriptional factor and repressor of E-cadherin is well known for its role in cellular invasion. It can regulate epithelial to mesenchymal transition (EMT) during embryonic development and in epithelial cells. Snail also mediates tumor progression and metastases. Silencing of...

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Detalles Bibliográficos
Autores principales: Abdulkhalek, Samar, Geen, Olivia D, Brodhagen, Lacey, Haxho, Fiona, Alghamdi, Farah, Allison, Stephanie, Simmons, Duncan J, O'Shea, Leah K, Neufeld, Ronald J, Szewczuk, Myron R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884043/
https://www.ncbi.nlm.nih.gov/pubmed/26932374
http://dx.doi.org/10.1186/s40169-014-0028-z