Improved production of poly(lactic acid)-like polyester based on metabolite analysis to address the rate-limiting step

The biosynthesis of poly(lactic acid) (PLA)-like polymers, composed of >99 mol% lactate and a trace amount of 3-hydroxybutyrate, in engineered Corynebacterium glutamicum consists of two steps; the generation of the monomer substrate lactyl-coenzyme A (CoA) and the polyhydroxyalkanoate (PHA) synth...

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Detalles Bibliográficos
Autores principales: Matsumoto, Ken’ichiro, Tobitani, Kota, Aoki, Shunsuke, Song, Yuyang, Ooi, Toshihiko, Taguchi, Seiichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884051/
https://www.ncbi.nlm.nih.gov/pubmed/26267112
http://dx.doi.org/10.1186/s13568-014-0083-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884051/
https://www.ncbi.nlm.nih.gov/pubmed/26267112
http://dx.doi.org/10.1186/s13568-014-0083-2

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