Sequence and Expression of Complement Factor H Gene Cluster Variants and Their Roles in Age-Related Macular Degeneration Risk

PURPOSE: To investigate how potentially functional genetic variants are coinherited on each of four common complement factor H (CFH) and CFH-related gene haplotypes and to measure expression of these genes in eye and liver tissues. METHODS: We sequenced the CFH region in four individuals (one homozy...

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Detalles Bibliográficos
Autores principales: Hughes, Anne E., Bridgett, Stephen, Meng, Weihua, Li, Mingyao, Curcio, Christine A., Stambolian, Dwight, Bradley, Declan T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2016
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884056/
https://www.ncbi.nlm.nih.gov/pubmed/27196323
http://dx.doi.org/10.1167/iovs.15-18744

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884056/
https://www.ncbi.nlm.nih.gov/pubmed/27196323
http://dx.doi.org/10.1167/iovs.15-18744

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