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NFκB is a central regulator of protein quality control in response to protein aggregation stresses via autophagy modulation

During cell life, proteins often misfold, depending on particular mutations or environmental changes, which may lead to protein aggregates that are toxic for the cell. Such protein aggregates are the root cause of numerous diseases called “protein conformational diseases,” such as myofibrillar myopa...

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Detalles Bibliográficos
Autores principales: Nivon, Mathieu, Fort, Loïc, Muller, Pascale, Richet, Emma, Simon, Stéphanie, Guey, Baptiste, Fournier, Maëlenn, Arrigo, André-Patrick, Hetz, Claudio, Atkin, Julie D., Kretz-Remy, Carole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884063/
https://www.ncbi.nlm.nih.gov/pubmed/27075172
http://dx.doi.org/10.1091/mbc.E15-12-0835