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NFκB is a central regulator of protein quality control in response to protein aggregation stresses via autophagy modulation
During cell life, proteins often misfold, depending on particular mutations or environmental changes, which may lead to protein aggregates that are toxic for the cell. Such protein aggregates are the root cause of numerous diseases called “protein conformational diseases,” such as myofibrillar myopa...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884063/ https://www.ncbi.nlm.nih.gov/pubmed/27075172 http://dx.doi.org/10.1091/mbc.E15-12-0835 |