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Synergistic role of fission yeast Alp16(GCP6) and Mzt1(MOZART1) in γ-tubulin complex recruitment to mitotic spindle pole bodies and spindle assembly

In fission yeast, γ-tubulin ring complex (γTuRC)–specific components Gfh1(GCP4), Mod21(GCP5), and Alp16(GCP6) are nonessential for cell growth. Of these deletion mutants, only alp16Δ shows synthetic lethality with temperature-sensitive mutants of Mzt1(MOZART1), a component of the γTuRC required for...

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Detalles Bibliográficos
Autores principales: Masuda, Hirohisa, Toda, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884066/
https://www.ncbi.nlm.nih.gov/pubmed/27053664
http://dx.doi.org/10.1091/mbc.E15-08-0577