Cargando…

Synergistic role of fission yeast Alp16(GCP6) and Mzt1(MOZART1) in γ-tubulin complex recruitment to mitotic spindle pole bodies and spindle assembly

In fission yeast, γ-tubulin ring complex (γTuRC)–specific components Gfh1(GCP4), Mod21(GCP5), and Alp16(GCP6) are nonessential for cell growth. Of these deletion mutants, only alp16Δ shows synthetic lethality with temperature-sensitive mutants of Mzt1(MOZART1), a component of the γTuRC required for...

Descripción completa

Detalles Bibliográficos
Autores principales:	Masuda, Hirohisa, Toda, Takashi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2016
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884066/ https://www.ncbi.nlm.nih.gov/pubmed/27053664 http://dx.doi.org/10.1091/mbc.E15-08-0577

Ejemplares similares

Mzt1/Tam4, a fission yeast MOZART1 homologue, is an essential component of the γ-tubulin complex and directly interacts with GCP3(Alp6)
por: Dhani, Deepsharan K., et al.
Publicado: (2013)

Targeting Alp7/TACC to the spindle pole body is essential for mitotic spindle assembly in fission yeast
por: Tang, Ngang Heok, et al.
Publicado: (2014)

Fission yeast MOZART1/Mzt1 is an essential γ-tubulin complex component required for complex recruitment to the microtubule organizing center, but not its assembly
por: Masuda, Hirohisa, et al.
Publicado: (2013)

Fission yeast Pcp1 links polo kinase-mediated mitotic entry to γ-tubulin-dependent spindle formation
por: Fong, Chii Shyang, et al.
Publicado: (2010)

Csi1p recruits alp7p/TACC to the spindle pole bodies for bipolar spindle formation
por: Zheng, Fan, et al.
Publicado: (2014)

Tem1 localization to the spindle pole bodies is essential for mitotic exit and impairs spindle checkpoint function
por: Valerio-Santiago, Mauricio, et al.
Publicado: (2011)

Asymmetry of the Budding Yeast Tem1 GTPase at Spindle Poles Is Required for Spindle Positioning But Not for Mitotic Exit
por: Scarfone, Ilaria, et al.
Publicado: (2015)

Naegleria’s mitotic spindles are built from unique tubulins and highlight core spindle features
por: Velle, Katrina B., et al.
Publicado: (2022)

gamma-Tubulin-like Tub4p of Saccharomyces cerevisiae is associated with the spindle pole body substructures that organize microtubules and is required for mitotic spindle formation
Publicado: (1996)

The product of the spindle formation gene sad1+ associates with the fission yeast spindle pole body and is essential for viability
Publicado: (1995)

Distribution of γ-tubulin ring complex at the Schizosaccharomyces pombe spindle pole
por: Saha, Sajjita, et al.
Publicado: (2021)

Automated tracking of mitotic spindle pole positions shows that LGN is required for spindle rotation but not orientation maintenance
por: Corrigan, Adam M, et al.
Publicado: (2013)

The Msd1–Wdr8–Pkl1 complex anchors microtubule minus ends to fission yeast spindle pole bodies
por: Yukawa, Masashi, et al.
Publicado: (2015)

Components of the yeast spindle and spindle pole body
Publicado: (1990)

Spindle pole body components are reorganized during fission yeast meiosis
por: Ohta, Midori, et al.
Publicado: (2012)

Mitotic Spindle Poles are Organized by Structural and Motor Proteins in Addition to Centrosomes
por: Gaglio, Tirso, et al.
Publicado: (1997)

Opposing motor activities are required for the organization of the mammalian mitotic spindle pole
Publicado: (1996)

Aurora at the pole and equator: overlapping functions of Aurora kinases in the mitotic spindle
por: Hochegger, Helfrid, et al.
Publicado: (2013)

Spindle pole bodies function as signal amplifiers in the Mitotic Exit Network
por: Campbell, Ian W., et al.
Publicado: (2020)

Mitotic cell death induction by targeting the mitotic spindle with tubulin-inhibitory indole derivative molecules
por: Cesare, Erica Di, et al.
Publicado: (2017)

Kinetochore-mediated outward force promotes spindle pole separation in fission yeast
por: Shirasugi, Yutaka, et al.
Publicado: (2019)

Physical determinants of bipolar mitotic spindle assembly and stability in fission yeast
por: Blackwell, Robert, et al.
Publicado: (2017)

Mechanisms for focusing mitotic spindle poles by minus end–directed motor proteins
por: Goshima, Gohta, et al.
Publicado: (2005)

TOG–tubulin binding specificity promotes microtubule dynamics and mitotic spindle formation
por: Byrnes, Amy E., et al.
Publicado: (2017)

Adducin-1 moonlights at the mitotic spindle
por: Leslie, Mitch
Publicado: (2014)

Cytoplasmic dynein/dynactin drives kinetochore protein transport to the spindle poles and has a role in mitotic spindle checkpoint inactivation
por: Howell, B.J., et al.
Publicado: (2001)

DDA3 recruits microtubule depolymerase Kif2a to spindle poles and controls spindle dynamics and mitotic chromosome movement
por: Jang, Chang-Young, et al.
Publicado: (2008)

Building a spindle pole
por: Wells, William A.
Publicado: (2002)

Concentrating on the mitotic spindle
por: Maddox, Paul S., et al.
Publicado: (2015)

Mitotic-Spindle Organizing Protein MztA Mediates Septation Signaling by Suppressing the Regulatory Subunit of Protein Phosphatase 2A-ParA in Aspergillus nidulans
por: Jiang, Ping, et al.
Publicado: (2018)

Force and the spindle: Mechanical cues in mitotic spindle orientation
por: Nestor-Bergmann, Alexander, et al.
Publicado: (2014)

Regulation of spindle pole body assembly and cytokinesis by the centrin-binding protein Sfi1 in fission yeast
por: Lee, I-Ju, et al.
Publicado: (2014)

The Saccharomyces cerevisiae spindle pole body duplication gene MPS1 is part of a mitotic checkpoint
Publicado: (1996)

Dnt1 acts as a mitotic inhibitor of the spindle checkpoint protein dma1 in fission yeast
por: Wang, Yamei, et al.
Publicado: (2012)

Mitotic spindle assembly and γ-tubulin localisation depend on the integral nuclear membrane protein Samp1
por: Larsson, Veronica J., et al.
Publicado: (2018)

A novel mitotic spindle pole component that originates from the cytoplasm during prophase
Publicado: (1986)

A comparison of the distribution of actin and tubulin in the mammalian mitotic spindle as seen by indirect immunofluorescence
Publicado: (1977)

GROWTH AND LABILITY OF CHAETOPTERUS OOCYTE MITOTIC SPINDLES ISOLATED IN THE PRESENCE OF PORCINE BRAIN TUBULIN
por: Inoué, Shinya, et al.
Publicado: (1974)

Polyglutamylated Tubulin Binding Protein C1orf96/CSAP Is Involved in Microtubule Stabilization in Mitotic Spindles
por: Ohta, Shinya, et al.
Publicado: (2015)

ACTIN AND MYOSIN IN THE MITOTIC SPINDLE
por: Robinson, Richard
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_b0fjaa1oj6cini0s9l71plongh