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Synthetic long read sequencing reveals the composition and intraspecies diversity of the human microbiome

Identifying bacterial strains in metagenome and microbiome samples using computational analyses of short-read sequence remains a difficult problem. Here, we present an analysis of a human gut microbiome using on Tru-seq synthetic long reads combined with new computational tools for metagenomic long-...

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Detalles Bibliográficos
Autores principales: Kuleshov, Volodymyr, Jiang, Chao, Zhou, Wenyu, Jahanbani, Fereshteh, Batzoglou, Serafim, Snyder, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884093/
https://www.ncbi.nlm.nih.gov/pubmed/26655498
http://dx.doi.org/10.1038/nbt.3416