SIRT7 promotes genome integrity and modulates non‐homologous end joining DNA repair

Sirtuins, a family of protein deacetylases, promote cellular homeostasis by mediating communication between cells and environment. The enzymatic activity of the mammalian sirtuin SIRT7 targets acetylated lysine in the N‐terminal tail of histone H3 (H3K18Ac), thus modulating chromatin structure and t...

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Detalles Bibliográficos
Autores principales: Vazquez, Berta N, Thackray, Joshua K, Simonet, Nicolas G, Kane‐Goldsmith, Noriko, Martinez‐Redondo, Paloma, Nguyen, Trang, Bunting, Samuel, Vaquero, Alejandro, Tischfield, Jay A, Serrano, Lourdes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884211/
https://www.ncbi.nlm.nih.gov/pubmed/27225932
http://dx.doi.org/10.15252/embj.201593499

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884211/
https://www.ncbi.nlm.nih.gov/pubmed/27225932
http://dx.doi.org/10.15252/embj.201593499

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