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Determination of the Role of CBP- and p300-Mediated Wnt Signaling on Colonic Cells
BACKGROUND: The Wnt signaling pathway, mediated through active beta-catenin, is responsible for initiating the majority of cases of human colorectal cancer (CRC), and we have previously shown that hyperactivation of this pathway by histone deacetylase inhibitors (HDACis), such as butyrate, can induc...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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JMIR Publications Inc.
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884266/ https://www.ncbi.nlm.nih.gov/pubmed/27177606 http://dx.doi.org/10.2196/resprot.5495 |