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Cogena, a novel tool for co-expressed gene-set enrichment analysis, applied to drug repositioning and drug mode of action discovery

BACKGROUND: Drug repositioning, finding new indications for existing drugs, has gained much recent attention as a potentially efficient and economical strategy for accelerating new therapies into the clinic. Although improvement in the sensitivity of computational drug repositioning methods has iden...

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Detalles Bibliográficos
Autores principales: Jia, Zhilong, Liu, Ying, Guan, Naiyang, Bo, Xiaochen, Luo, Zhigang, Barnes, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884357/
https://www.ncbi.nlm.nih.gov/pubmed/27234029
http://dx.doi.org/10.1186/s12864-016-2737-8