Cargando…

Kynurenine metabolic balance is disrupted in the hippocampus following peripheral lipopolysaccharide challenge

BACKGROUND: Inflammation increases the risk of developing depression-related symptoms, and tryptophan metabolism is an important mediator of these behavior changes. Peripheral immune activation results in central up-regulation of pro-inflammatory cytokine expression, microglia activation, and the pr...

Descripción completa

Detalles Bibliográficos
Autores principales: Parrott, Jennifer M., Redus, Laney, O’Connor, Jason C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884395/
https://www.ncbi.nlm.nih.gov/pubmed/27233247
http://dx.doi.org/10.1186/s12974-016-0590-y