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Kynurenine metabolic balance is disrupted in the hippocampus following peripheral lipopolysaccharide challenge
BACKGROUND: Inflammation increases the risk of developing depression-related symptoms, and tryptophan metabolism is an important mediator of these behavior changes. Peripheral immune activation results in central up-regulation of pro-inflammatory cytokine expression, microglia activation, and the pr...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884395/ https://www.ncbi.nlm.nih.gov/pubmed/27233247 http://dx.doi.org/10.1186/s12974-016-0590-y |