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Altered DNA base excision repair profile in brain tissue and blood in Alzheimer’s disease

BACKGROUND: Alzheimer’s disease (AD) is a progressive, multifactorial neurodegenerative disorder that is the main cause of dementia globally. AD is associated with increased oxidative stress, resulting from imbalance in production and clearance of reactive oxygen species (ROS). ROS can damage DNA an...

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Detalles Bibliográficos
Autores principales: Lillenes, Meryl S., Rabano, Alberto, Støen, Mari, Riaz, Tahira, Misaghian, Dorna, Møllersen, Linda, Esbensen, Ying, Günther, Clara-Cecilie, Selnes, Per, Stenset, Vidar T. V., Fladby, Tormod, Tønjum, Tone
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884418/
https://www.ncbi.nlm.nih.gov/pubmed/27234294
http://dx.doi.org/10.1186/s13041-016-0237-z