Cargando…

Altered DNA base excision repair profile in brain tissue and blood in Alzheimer’s disease

BACKGROUND: Alzheimer’s disease (AD) is a progressive, multifactorial neurodegenerative disorder that is the main cause of dementia globally. AD is associated with increased oxidative stress, resulting from imbalance in production and clearance of reactive oxygen species (ROS). ROS can damage DNA an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lillenes, Meryl S., Rabano, Alberto, Støen, Mari, Riaz, Tahira, Misaghian, Dorna, Møllersen, Linda, Esbensen, Ying, Günther, Clara-Cecilie, Selnes, Per, Stenset, Vidar T. V., Fladby, Tormod, Tønjum, Tone
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884418/ https://www.ncbi.nlm.nih.gov/pubmed/27234294 http://dx.doi.org/10.1186/s13041-016-0237-z

Ejemplares similares

Effects of cerebrovascular disease on amyloid precursor protein metabolites in cerebrospinal fluid
por: Selnes, Per, et al.
Publicado: (2010)

The Role of Mitochondrial Dysfunction in the Progression of Alzheimer’s Disease
por: Desler, Claus, et al.
Publicado: (2018)

Cerebrospinal fluid markers in Creutzfeldt-Jakob disease
por: Skinningsrud, Anders, et al.
Publicado: (2008)

[(18)F]-Flutemetamol Uptake in Cortex and White Matter: Comparison with Cerebrospinal Fluid Biomarkers and [(18)F]-Fludeoxyglucose
por: Kalheim, Lisa Flem, et al.
Publicado: (2018)

Correlates of Subjective and Mild Cognitive Impairment: Depressive Symptoms and CSF Biomarkers
por: Grambaite, Ramune, et al.
Publicado: (2013)

Amyloid Dysmetabolism Relates to Reduced Glucose Uptake in White Matter Hyperintensities
por: Kalheim, Lisa Flem, et al.
Publicado: (2016)

Biomarkers in subtypes of mild cognitive impairment and subjective cognitive decline
por: Eliassen, Carl F., et al.
Publicado: (2017)

Comparative proteomic analysis of Neisseria meningitidis wildtype and dprA null mutant strains links DNA processing to pilus biogenesis
por: Beyene, Getachew Tesfaye, et al.
Publicado: (2017)

Spatial Transcriptomics Reveals Genes Associated with Dysregulated Mitochondrial Functions and Stress Signaling in Alzheimer Disease
por: Navarro, José Fernández, et al.
Publicado: (2020)

Phenotype‐informed polygenic risk scores are associated with worse outcome in individuals at risk of Alzheimer's disease
por: Nordengen, Kaja, et al.
Publicado: (2022)

Amyloid Plaques and Symptoms of Depression Links to Medical Help-Seeking due to Subjective Cognitive Decline
por: Espenes, Ragna, et al.
Publicado: (2020)

White matter integrity and cognition in Parkinson's disease: a cross-sectional study
por: Auning, Eirik, et al.
Publicado: (2014)

CSF, Blood, and MRI Biomarkers in Skogholt’s Disease—A Rare Neurodegenerative Disease in a Norwegian Kindred
por: Aspli, Klaus Thanke, et al.
Publicado: (2023)

Neuropsychological Profiles in Mild Cognitive Impairment due to Alzheimer’s and Parkinson’s Diseases
por: Hessen, Erik, et al.
Publicado: (2016)

Diffusion tensor and restriction spectrum imaging reflect different aspects of neurodegeneration in Parkinson’s disease
por: Hope, Tuva R., et al.
Publicado: (2019)

Segmenting white matter hyperintensities on isotropic three-dimensional Fluid Attenuated Inversion Recovery magnetic resonance images: Assessing deep learning tools on a Norwegian imaging database
por: Røvang, Martin Soria, et al.
Publicado: (2023)

Cerebrospinal fluid neurogranin/β-site APP-cleaving enzyme 1 predicts cognitive decline in preclinical Alzheimer's disease
por: Kirsebom, Bjørn-Eivind, et al.
Publicado: (2018)

Hippocampal subfield atrophy in relation to cerebrospinal fluid biomarkers and cognition in early Parkinson’s disease: a cross-sectional study
por: Stav, Ane Løvli, et al.
Publicado: (2016)

Serum proteases prevent bacterial biofilm formation: role of kallikrein and plasmin
por: Arenas, Jesús, et al.
Publicado: (2021)

Glial activation and inflammation along the Alzheimer’s disease continuum
por: Nordengen, Kaja, et al.
Publicado: (2019)

Characterization of the meningococcal DNA glycosylase Fpg involved in base excision repair
por: Tibballs, Katrina L, et al.
Publicado: (2009)

Cerebrospinal Fluid Levels of Amyloid Beta 1-43 Mirror 1-42 in Relation to Imaging Biomarkers of Alzheimer’s Disease
por: Almdahl, Ina S., et al.
Publicado: (2017)

Characterization of the Neisseria meningitidis Helicase RecG
por: Beyene, Getachew Tesfaye, et al.
Publicado: (2016)

Proteome Profiling of Mycobacterium tuberculosis Cells Exposed to Nitrosative Stress
por: Birhanu, Alemayehu Godana, et al.
Publicado: (2022)

Stable cerebrospinal fluid neurogranin and β-site amyloid precursor protein cleaving enzyme 1 levels differentiate predementia Alzheimer’s disease patients
por: Kirsebom, Bjørn Eivind, et al.
Publicado: (2022)

Reduced expression of aquaporins in human intestinal mucosa in early stage inflammatory bowel disease
por: Ricanek, Petr, et al.
Publicado: (2015)

Medial Temporal Lobe Atrophy in Predementia Alzheimer’s Disease: A Longitudinal Multi-Site Study Comparing Staging and A/T/N in a Clinical Research Cohort1
por: Jarholm, Jonas Alexander, et al.
Publicado: (2023)

The helicase DinG responds to stress due to DNA double strand breaks
por: Frye, Stephan A., et al.
Publicado: (2017)

Impaired synaptic function is linked to cognition in Parkinson's disease
por: Selnes, Per, et al.
Publicado: (2017)

Brain amyloid and vascular risk are related to distinct white matter hyperintensity patterns
por: Pålhaugen, Lene, et al.
Publicado: (2020)

Ample glycosylation in membrane and cell envelope proteins may explain the phenotypic diversity and virulence in the Mycobacterium tuberculosis complex
por: Birhanu, Alemayehu Godana, et al.
Publicado: (2019)

Kiss and Run – Phosphoglycerol Modifications of N. Meningitidis Pili Mediate Detachment
por: Tønjum, Tone, et al.
Publicado: (2011)

Comparative Proteomic Analysis of Mycobacterium tuberculosis Lineage 7 and Lineage 4 Strains Reveals Differentially Abundant Proteins Linked to Slow Growth and Virulence
por: Yimer, Solomon A., et al.
Publicado: (2017)

Lineage-Specific Proteomic Signatures in the Mycobacterium tuberculosis Complex Reveal Differential Abundance of Proteins Involved in Virulence, DNA Repair, CRISPR-Cas, Bioenergetics and Lipid Metabolism
por: Yimer, Solomon Abebe, et al.
Publicado: (2020)

Cerebrospinal fluid soluble TREM2 in aging and Alzheimer’s disease
por: Henjum, Kristi, et al.
Publicado: (2016)

Analyzing microglial-associated Aβ in Alzheimer’s disease transgenic mice with a novel mid-domain Aβ-antibody
por: Henjum, Kristi, et al.
Publicado: (2020)

Screening for Alzheimer’s Disease: Cognitive Impairment in Self-Referred and Memory Clinic-Referred Patients
por: Kirsebom, Bjørn-Eivind, et al.
Publicado: (2017)

Mathematical and Live Meningococcal Models for Simple Sequence Repeat Dynamics – Coherent Predictions and Observations
por: Alfsnes, Kristian, et al.
Publicado: (2014)

Dialects of the DNA Uptake Sequence in Neisseriaceae
por: Frye, Stephan A., et al.
Publicado: (2013)

Similar pattern of atrophy in early- and late-onset Alzheimer's disease
por: Eckerström, Carl, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_68f4m844keccvvf7ubjc8nte6u