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T cell-derived interleukin-10 is an important regulator of the Th17 response during lethal alphavirus encephalomyelitis
Neuroadapted Sindbis virus infection of mice causes T cell-mediated fatal encephalomyelitis. In the absence of IL-10, pathogenic Th17 cells are increased and disease is accelerated. Lymphoid and myeloid cell contributions to IL-10 production were determined using VertX IL-10 transcriptional eGFP rep...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier B.V.
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884611/ https://www.ncbi.nlm.nih.gov/pubmed/27235350 http://dx.doi.org/10.1016/j.jneuroim.2016.04.010 |