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Optimization of Thermoreversible In Situ Nasal Gel of Timolol Maleate

Nasal route had shown better systemic bioavailability due to its large surface area, porous endothelial membrane, high total blood flow, and avoidance of first-pass metabolism. Timolol maleate is a beta blocker used primarily in the treatment of hypertension. Drug undergoes extensive hepatic first-p...

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Detalles Bibliográficos
Autores principales: Jagdale, Swati, Shewale, Nirupama, Kuchekar, Bhanudas S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884840/
https://www.ncbi.nlm.nih.gov/pubmed/27293975
http://dx.doi.org/10.1155/2016/6401267