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Neuronal hemoglobin in mitochondria is reduced by forming a complex with α-synuclein in aging monkey brains

Neuronal hemoglobin (nHb) plays a critical role in maintaining normal mitochondrial functioning in the brain. However, in aging and Parkinson's disease (PD) brains, mitochondrial nHb levels are greatly reduced in neurons that accumulate α-synuclein (α-syn), suggesting a link between the two pro...

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Detalles Bibliográficos
Autores principales: Yang, Weiwei, Li, Xuran, Li, Xin, Li, Xuying, Yu, Shun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884930/
https://www.ncbi.nlm.nih.gov/pubmed/26824991
http://dx.doi.org/10.18632/oncotarget.7046