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Neuronal hemoglobin in mitochondria is reduced by forming a complex with α-synuclein in aging monkey brains
Neuronal hemoglobin (nHb) plays a critical role in maintaining normal mitochondrial functioning in the brain. However, in aging and Parkinson's disease (PD) brains, mitochondrial nHb levels are greatly reduced in neurons that accumulate α-synuclein (α-syn), suggesting a link between the two pro...
Autores principales: | Yang, Weiwei, Li, Xuran, Li, Xin, Li, Xuying, Yu, Shun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884930/ https://www.ncbi.nlm.nih.gov/pubmed/26824991 http://dx.doi.org/10.18632/oncotarget.7046 |
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