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Targeting Toll-like receptor 4 prevents cobalt-mediated inflammation

Cobalt-chrome alloy is a widely used biomaterial in joint replacements, dental implants and spinal rods. Although it is an effective and biocompatible material, adverse reactions to metal debris (ARMD) have arisen in a minority of patients, particularly in those with metal-on-metal bearing hip repla...

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Detalles Bibliográficos
Autores principales: Lawrence, Helen, Mawdesley, Amy Elizabeth, Holland, James Patrick, Kirby, John Andrew, Deehan, David John, Tyson-Capper, Alison Jane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884939/
https://www.ncbi.nlm.nih.gov/pubmed/26840091
http://dx.doi.org/10.18632/oncotarget.7105