Loss of CtIP disturbs homologous recombination repair and sensitizes breast cancer cells to PARP inhibitors

Breast cancer is one of the leading causes of death worldwide, and therefore, new and improved approaches for the treatment of breast cancer are desperately needed. CtIP (RBBP8) is a multifunctional protein that is involved in various cellular functions, including transcription, DNA replication, DNA...

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Detalles Bibliográficos
Autores principales: Wang, Junhui, Ding, Qianshan, Fujimori, Hiroaki, Motegi, Akira, Miki, Yoshio, Masutani, Mitsuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884948/
https://www.ncbi.nlm.nih.gov/pubmed/26713604
http://dx.doi.org/10.18632/oncotarget.6715

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884948/
https://www.ncbi.nlm.nih.gov/pubmed/26713604
http://dx.doi.org/10.18632/oncotarget.6715

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