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Loss of CtIP disturbs homologous recombination repair and sensitizes breast cancer cells to PARP inhibitors
Breast cancer is one of the leading causes of death worldwide, and therefore, new and improved approaches for the treatment of breast cancer are desperately needed. CtIP (RBBP8) is a multifunctional protein that is involved in various cellular functions, including transcription, DNA replication, DNA...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884948/ https://www.ncbi.nlm.nih.gov/pubmed/26713604 http://dx.doi.org/10.18632/oncotarget.6715 |