Valproic acid potentiates the anticancer activity of capecitabine in vitro and in vivo in breast cancer models via induction of thymidine phosphorylase expression

The prognosis of patients with metastatic breast cancer remains poor, and thus novel therapeutic approaches are needed. Capecitabine, which is commonly used for metastatic breast cancer in different settings, is an inactive prodrug that takes advantage of elevated levels of thymidine phosphorylase (...

Descripción completa

Detalles Bibliográficos
Autores principales: Terranova-Barberio, Manuela, Roca, Maria Serena, Zotti, Andrea Ilaria, Leone, Alessandra, Bruzzese, Francesca, Vitagliano, Carlo, Scogliamiglio, Giosuè, Russo, Domenico, D'Angelo, Giovanni, Franco, Renato, Budillon, Alfredo, Di Gennaro, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884949/
https://www.ncbi.nlm.nih.gov/pubmed/26735339
http://dx.doi.org/10.18632/oncotarget.6802

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884949/
https://www.ncbi.nlm.nih.gov/pubmed/26735339
http://dx.doi.org/10.18632/oncotarget.6802

Ejemplares similares