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Hepatitis B virus X protein binding to hepsin promotes C3 production by inducing IL-6 secretion from hepatocytes

Hepatitis B virus (HBV) X protein (HBx) is an important effector for HBV-associated pathogenesis. In this study, we identified hepsin as an HBx-interacting protein and investigated the effects of hepsin on HBx-mediated complement component 3 (C3) secretion in hepatocytes. In vivo and in vitro bindin...

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Detalles Bibliográficos
Autores principales: Zhang, Mingming, Gu, Jianxin, Zhang, Chunyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884954/
https://www.ncbi.nlm.nih.gov/pubmed/26760961
http://dx.doi.org/10.18632/oncotarget.6846