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ROS1 copy number alterations are frequent in non-small cell lung cancer

OBJECTIVES: We aimed to determine the prevalence and partners of ROS1 rearrangements, to explore the correlation between FISH and IHC assays, and to investigate clinical implications of ROS1 copy number alterations (CNAs). METHODS: A total of 314 NSCLC patients were screened using ROS1 FISH break-ap...

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Detalles Bibliográficos
Autores principales: Clavé, Sergi, Gimeno, Javier, Muñoz-Mármol, Ana M., Vidal, Joana, Reguart, Noemí, Carcereny, Enric, Pijuan, Lara, Menéndez, Sílvia, Taus, Álvaro, Mate, José Luís, Serrano, Sergio, Albanell, Joan, Espinet, Blanca, Arriola, Edurne, Salido, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884972/
https://www.ncbi.nlm.nih.gov/pubmed/26783962
http://dx.doi.org/10.18632/oncotarget.6921