Identification of approved and investigational drugs that inhibit hypoxia-inducible factor-1 signaling

One of the requirements for tumor development is blood supply, most often driven by hypoxia-induced angiogenesis. Hypoxia induces the stabilization of hypoxia-inducible factor-1 alpha (HIF-1α), which induces expression of an angiogenic factor, vascular endothelial growth factor (VEGF). The purpose o...

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Detalles Bibliográficos
Autores principales: Hsu, Chia-Wen, Huang, Ruili, Khuc, Thai, Shou, David, Bullock, Joshua, Grooby, Suzanne, Griffin, Sue, Zou, Chaozhong, Little, Annette, Astley, Holly, Xia, Menghang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884984/
https://www.ncbi.nlm.nih.gov/pubmed/26882567
http://dx.doi.org/10.18632/oncotarget.6995

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884984/
https://www.ncbi.nlm.nih.gov/pubmed/26882567
http://dx.doi.org/10.18632/oncotarget.6995

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