TSGΔ154-1054 splice variant increases TSG101 oncogenicity by inhibiting its E3-ligase-mediated proteasomal degradation

Tumor susceptibility gene 101 (TSG101) elicits an array of cellular functions, including promoting cytokinesis, cell cycle progression and proliferation, as well as facilitating endosomal trafficking and viral budding. TSG101 protein is highly and aberrantly expressed in various human cancers. Speci...

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Detalles Bibliográficos
Autores principales: Chua, Huey-Huey, Huang, Chiun-Sheng, Weng, Pei-Lun, Yeh, Te-Huei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884989/
https://www.ncbi.nlm.nih.gov/pubmed/26811492
http://dx.doi.org/10.18632/oncotarget.6973

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884989/
https://www.ncbi.nlm.nih.gov/pubmed/26811492
http://dx.doi.org/10.18632/oncotarget.6973

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