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TSGΔ154-1054 splice variant increases TSG101 oncogenicity by inhibiting its E3-ligase-mediated proteasomal degradation
Tumor susceptibility gene 101 (TSG101) elicits an array of cellular functions, including promoting cytokinesis, cell cycle progression and proliferation, as well as facilitating endosomal trafficking and viral budding. TSG101 protein is highly and aberrantly expressed in various human cancers. Speci...
Autores principales: | Chua, Huey-Huey, Huang, Chiun-Sheng, Weng, Pei-Lun, Yeh, Te-Huei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884989/ https://www.ncbi.nlm.nih.gov/pubmed/26811492 http://dx.doi.org/10.18632/oncotarget.6973 |
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