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microRNAs regulate TAL1 expression in T-cell acute lymphoblastic leukemia

The transcription factor TAL1 is a proto-oncogene whose aberrant expression in committed T-cell precursors is associated with the development of T-cell acute lymphoblastic leukemia (T-ALL). The mechanisms leading to aberrant activation of TAL1 in T-ALL patients who lack chromosomal rearrangements in...

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Detalles Bibliográficos
Autores principales: Correia, Nádia C., Melão, Alice, Póvoa, Vanda, Sarmento, Leonor, de Cedrón, Marta Gómez, Malumbres, Marcos, Enguita, Francisco J., Barata, João T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884991/
https://www.ncbi.nlm.nih.gov/pubmed/26882564
http://dx.doi.org/10.18632/oncotarget.6987