Whole exome and targeted deep sequencing identify genome-wide allelic loss and frequent SETDB1 mutations in malignant pleural mesotheliomas

Malignant pleural mesothelioma (MPM), a rare malignancy with a poor prognosis, is mainly caused by exposure to asbestos or other organic fibers, but the underlying genetic mechanism is not fully understood. Genetic alterations and causes for multiple primary cancer development including MPM are unkn...

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Detalles Bibliográficos
Autores principales: Kang, Hio Chung, Kim, Hong Kwan, Lee, Sharon, Mendez, Pedro, Kim, James Wansoo, Woodard, Gavitt, Yoon, Jun-Hee, Jen, Kuang-Yu, Fang, Li Tai, Jones, Kirk, Jablons, David M., Kim, Il-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884995/
https://www.ncbi.nlm.nih.gov/pubmed/26824986
http://dx.doi.org/10.18632/oncotarget.7032

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884995/
https://www.ncbi.nlm.nih.gov/pubmed/26824986
http://dx.doi.org/10.18632/oncotarget.7032

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