Docking Simulation of the Binding Interactions of Saxitoxin Analogs Produced by the Marine Dinoflagellate Gymnodinium catenatum to the Voltage-Gated Sodium Channel Na(v)1.4

Saxitoxin (STX) and its analogs are paralytic alkaloid neurotoxins that block the voltage-gated sodium channel pore (Na(v)), impeding passage of Na(+) ions into the intracellular space, and thereby preventing the action potential in the peripheral nervous system and skeletal muscle. The marine dinof...

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Detalles Bibliográficos
Autores principales: Durán-Riveroll, Lorena M., Cembella, Allan D., Band-Schmidt, Christine J., Bustillos-Guzmán, José J., Correa-Basurto, José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4885044/
https://www.ncbi.nlm.nih.gov/pubmed/27164145
http://dx.doi.org/10.3390/toxins8050129

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4885044/
https://www.ncbi.nlm.nih.gov/pubmed/27164145
http://dx.doi.org/10.3390/toxins8050129

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