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Determination of Asymmetric and Symmetric Dimethylarginine in Serum from Patients with Chronic Kidney Disease: UPLC-MS/MS versus ELISA

Asymmetric dimethylarginine (ADMA), an endogenous inhibitor of nitric oxide (NO) synthesis, and its structural isomer symmetric dimethylarginine (SDMA) are uremic toxins accumulating in chronic kidney disease (CKD) patients. The objective of this study was to develop and validate a robust UPLC-MS/MS...

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Detalles Bibliográficos
Autores principales: Boelaert, Jente, Schepers, Eva, Glorieux, Griet, Eloot, Sunny, Vanholder, Raymond, Lynen, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4885064/
https://www.ncbi.nlm.nih.gov/pubmed/27187471
http://dx.doi.org/10.3390/toxins8050149