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The Rabies Virus L Protein Catalyzes mRNA Capping with GDP Polyribonucleotidyltransferase Activity

The large (L) protein of rabies virus (RABV) plays multiple enzymatic roles in viral RNA synthesis and processing. However, none of its putative enzymatic activities have been directly demonstrated in vitro. In this study, we expressed and purified a recombinant form of the RABV L protein and verifi...

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Detalles Bibliográficos
Autores principales: Ogino, Minako, Ito, Naoto, Sugiyama, Makoto, Ogino, Tomoaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4885099/
https://www.ncbi.nlm.nih.gov/pubmed/27213429
http://dx.doi.org/10.3390/v8050144