HACE1 Negatively Regulates Virus-Triggered Type I IFN Signaling by Impeding the Formation of the MAVS-TRAF3 Complex

During virus infection, the cascade signaling pathway that leads to the production of proinflammatory cytokines is controlled at multiple levels to avoid detrimental overreaction. HACE1 has been characterized as an important tumor suppressor. Here, we identified HACE1 as an important negative regula...

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Detalles Bibliográficos
Autores principales: Mao, He-Ting, Wang, Yan, Cai, Juan, Meng, Jun-Ling, Zhou, Yu, Pan, Yu, Qian, Xiao-Ping, Zhang, Yu, Zhang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4885101/
https://www.ncbi.nlm.nih.gov/pubmed/27213432
http://dx.doi.org/10.3390/v8050146

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4885101/
https://www.ncbi.nlm.nih.gov/pubmed/27213432
http://dx.doi.org/10.3390/v8050146

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