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Novel monoclonal antibody against beta 1 integrin enhances cisplatin efficacy in human lung adenocarcinoma cells

The use of anti-beta 1 integrin monoclonal antibody in lung cancer treatment has proven beneficial. Here, we developed a novel monoclonal antibody (mAb), called P5, by immunizing mice with human peripheral blood mononuclear cells (PBMC). Its anti-tumor effect is now being tested, in a clinical phase...

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Detalles Bibliográficos
Autores principales: Kim, Min-Young, Cho, Woon-Dong, Hong, Kwon Pyo, Choi, Da Bin, Hong, Jeong won, Kim, Soseul, Moon, Yoo Ri, Son, Seung-Myoung, Lee, Ok-Jun, Lee, Ho-Chang, Song, Hyung Geun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial Department of Journal of Biomedical Research 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4885170/
https://www.ncbi.nlm.nih.gov/pubmed/27533932
http://dx.doi.org/10.7555/JBR.30.2016K0005