Mechanistic Modeling of the Effects of Acidosis on Thrombin Generation

BACKGROUND: Acidosis, a frequent complication of trauma and complex surgery, results from tissue hypoperfusion and IV resuscitation with acidic fluids. While acidosis is known to inhibit the function of distinct enzymatic reactions, its cumulative effect on the blood coagulation system is not fully...

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Detalles Bibliográficos
Autores principales: Mitrophanov, Alexander Y., Rosendaal, Frits R., Reifman, Jaques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2015
Materias:
30
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4885548/
https://www.ncbi.nlm.nih.gov/pubmed/25839182
http://dx.doi.org/10.1213/ANE.0000000000000733

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4885548/
https://www.ncbi.nlm.nih.gov/pubmed/25839182
http://dx.doi.org/10.1213/ANE.0000000000000733

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