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Mechanistic Modeling of the Effects of Acidosis on Thrombin Generation
BACKGROUND: Acidosis, a frequent complication of trauma and complex surgery, results from tissue hypoperfusion and IV resuscitation with acidic fluids. While acidosis is known to inhibit the function of distinct enzymatic reactions, its cumulative effect on the blood coagulation system is not fully...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Lippincott Williams & Wilkins
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4885548/ https://www.ncbi.nlm.nih.gov/pubmed/25839182 http://dx.doi.org/10.1213/ANE.0000000000000733 |