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Dexamethasone and insulin activate serum and glucocorticoid‐inducible kinase 1 (SGK1) via different molecular mechanisms in cortical collecting duct cells

Serum and glucocorticoid‐inducible kinase 1 (SGK1) is a protein kinase that contributes to the hormonal control of renal Na(+) retention by regulating the abundance of epithelial Na(+) channels (ENaC) at the apical surface of the principal cells of the cortical collecting duct (CCD). Although glucoc...

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Detalles Bibliográficos
Autores principales: Mansley, Morag K., Watt, Gordon B., Francis, Sarah L., Walker, David J., Land, Stephen C., Bailey, Matthew A., Wilson, Stuart M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886164/
https://www.ncbi.nlm.nih.gov/pubmed/27225626
http://dx.doi.org/10.14814/phy2.12792