Formulation optimization of Docetaxel loaded self-emulsifying drug delivery system to enhance bioavailability and anti-tumor activity

Poor bioavailability of Docetaxel (DCT) arising due to its low aqueous solubility and permeability limits its clinical utility. The aim of the present study was to develop DCT loaded self-emulsified drug delivery systems (D-SEDDS) and evaluate its potential ability to improve the oral bioavailabilit...

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Detalles Bibliográficos
Autores principales: Valicherla, Guru R., Dave, Kandarp M., Syed, Anees A., Riyazuddin, Mohammed, Gupta, Anand P., Singh, Akhilesh, Wahajuddin, Mitra, Kalyan, Datta, Dipak, Gayen, Jiaur R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886259/
https://www.ncbi.nlm.nih.gov/pubmed/27241877
http://dx.doi.org/10.1038/srep26895

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886259/
https://www.ncbi.nlm.nih.gov/pubmed/27241877
http://dx.doi.org/10.1038/srep26895

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