Cargando…
Two distinct voltage-sensing domains control voltage sensitivity and kinetics of current activation in Ca(V)1.1 calcium channels
Alternative splicing of the skeletal muscle Ca(V)1.1 voltage-gated calcium channel gives rise to two channel variants with very different gating properties. The currents of both channels activate slowly; however, insertion of exon 29 in the adult splice variant Ca(V)1.1a causes an ∼30-mV right shift...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2016
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886277/ https://www.ncbi.nlm.nih.gov/pubmed/27185857 http://dx.doi.org/10.1085/jgp.201611568 |