Cargando…

TRPM7 is a molecular substrate of ATP-evoked P2X7-like currents in tumor cells

Within the ion channel–coupled purine receptor (P2X) family, P2X7 has gained particular interest because of its role in immune responses and in the growth control of several malignancies. Typical hallmarks of P2X7 are nonselective and noninactivating cation currents that are elicited by high concent...

Descripción completa

Detalles Bibliográficos
Autores principales: Nörenberg, Wolfgang, Plötz, Tanja, Sobottka, Helga, Chubanov, Vladimir, Mittermeier, Lorenz, Kalwa, Hermann, Aigner, Achim, Schaefer, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886280/
https://www.ncbi.nlm.nih.gov/pubmed/27185858
http://dx.doi.org/10.1085/jgp.201611595