Cargando…
TRPM7 is a molecular substrate of ATP-evoked P2X7-like currents in tumor cells
Within the ion channel–coupled purine receptor (P2X) family, P2X7 has gained particular interest because of its role in immune responses and in the growth control of several malignancies. Typical hallmarks of P2X7 are nonselective and noninactivating cation currents that are elicited by high concent...
Autores principales: | Nörenberg, Wolfgang, Plötz, Tanja, Sobottka, Helga, Chubanov, Vladimir, Mittermeier, Lorenz, Kalwa, Hermann, Aigner, Achim, Schaefer, Michael |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886280/ https://www.ncbi.nlm.nih.gov/pubmed/27185858 http://dx.doi.org/10.1085/jgp.201611595 |
Ejemplares similares
-
TRPM6 and TRPM7 differentially contribute to the relief of heteromeric TRPM6/7 channels from inhibition by cytosolic Mg(2+) and Mg·ATP
por: Ferioli, Silvia, et al.
Publicado: (2017) -
Structural mechanism of TRPM7 channel regulation by intracellular magnesium
por: Schmidt, Eva, et al.
Publicado: (2022) -
Mapping TRPM7 Function by NS8593
por: Chubanov, Vladimir, et al.
Publicado: (2020) -
TRPM7 is the central gatekeeper of intestinal mineral absorption essential for postnatal survival
por: Mittermeier, Lorenz, et al.
Publicado: (2019) -
Natural and Synthetic Modulators of the TRPM7 Channel
por: Chubanov, Vladimir, et al.
Publicado: (2014)